강승구 교수
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강승구 교수

강승구 교수님
강승구 교수님
  • 전공 : 세포면역학
  • 연구분야 : 면역세포 분화 및 이동과정 연구, CAR-T 제작 및 활용
  • 연락처 : 033) 250-8386
  • 이메일 : sgkang@kangwon.ac.kr
학력
  • 1997 연세대학교 학사 (생물학)
  • 2000 연세대학교 석사 (분자면역학)
  • 2009 Purdue University 박사 (면역학, 병리학)
주요경력
  • 2009 ~ 2009 Postdoctoral Fellow, Purdue University, IN
  • 2010 ~ 2015 Research Associate, The Scripps Research Institute, CA
  • 2015 ~ Current 조교수, 강원대학교 의생명과학대학 시스템면역과학과
주요경력
연구실적 (논문 및 특허실적)
  • Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schn?lzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E, SIRT1 deacetylates RORγt and enhances Th17 cell generation. J Exp Med. 2015 May 4;212(5):607-17
  • Park J, Kim M, Kang SG, Jannasch AH, Cooper B, Patterson J, Kim CH. Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway. Mucosal Immunol. 2015 Jan;8(1):80-93.
  • Jin HY, Oda H, Lai M, Skalsky RL, Bethel K, Shepherd J, Kang SG, Liu WH, Sabouri-Ghomi M, Cullen BR, Rajewsky K, Xiao C. MicroRNA 17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways. The EMBO Journal, 2013 Aug 28;32(17):2377-91
  • Shim EJ*, Bang BR*, Kang SG*, Ma J, Otsuka M, Kang J, Stahl M, Han J, Xiao C, Vallance BA, Kang YJ*. Activation of p38a in T cells regulates the intestinal host defense against attaching and effacing bacterial infections. J Immunol. 2013 Sep 1;191(5):2764-70 (*Equal contribution)
  • Kang SG*, Liu W*, Lu P*, Jin HY, Lim HW, Shepherd J, Fremgen D, Verdin E, Qi H, Oldstone M, Teijaro J, Xiao C. MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation. Nature Immunology. 2013 Aug;14(8):849-57. (*Equal contribution)
  • Kim MH, Kang SG, Park JH, Yanagisawa M, Kim CH. Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice. Gastroenterology, 2013 Aug;145(2):396-406
  • Kang SG, Park J, Cho JY, Ulrich B, Kim CH. Complementary roles of retinoic acid and TGF-beta1 in coordinated expression of mucosal integrins by T cells. Mucosal Immunol. 2011 Jan;4(1):66-82
  • Wang C, KangSG, Hogenesch H, Love PE, Kim CH. Retinoic Acid Determines the Precise Tissue Tropism of Inflammatory Th17 Cells in the Intestine. J Immunol. 2010 May 15;184(10):5519-26.
  • Betz BC, Jordan-Williams KL, Wang C, KangSG, Liao J, Logan MR, Kim CH, Taparowsky EJ. Batf coordinates multiple aspects of B and T cell function required for normal antibody responses. J Exp Med. 2010 May 10;207(5):933-42
  • Kang SG, Wang C, Matsumoto S, Kim CH. High and low vitamin A therapies induce distinct FoxP3+ regulatory T cell subsets and effectively control intestinal inflammation in mouse models. Gastroenterology. 2009 Oct;137(4):1391-402
  • Wang C*, Kang SG*, Lee J, Sun Z, Kim CH. The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut. Mucosal Immunol. 2009 Mar;2(2):173-83. (*Equal contribution)
  • Kang SG*, Lim HW*, Andrisani OM, Broxmeyer HE, Kim CH. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007 Sep 15;179(6):3724-33 (*Equal contribution)
  • Kang SG, Piniecki RJ, Lim HW, HogenEsch H, Braun SE, Wiebke E, Matsumoto S, Kim CH. Identification of a chemokine network that recruits FoxP3+ regulatory T cells to inflamed intestine. Gastroenterology 2007 Mar;132(3):966-81
  • Lee JH, KangSG, Kim CH. FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to non-lymphoid tissue homing receptors in secondary lymphoid tissues. J Immunol. 2007 Jan 1;178(1):301-11
  • Kim JR, Lim HW, KangSG. Hillsamer P, Kim CH. Human CD57+ germinal center-T cells are the major helpers for GC-B cells and induce class switch recombination. BMC Immunology 2005 Feb 4;6:3
  • Hong SY, Yoon WH, Park JH, KangSG, Ahn JH, and Lee TH. Involvement of two NF-kappa B binding elements in tumor necrosis factor alpha -, CD40-, and epstein-barr virus latent membrane protein 1-mediated induction of the cellular inhibitor of apoptosis protein 2 gene. J. Biol. Chem. 2000 Jun 16;275(24):18022-8
위로
24341 강원도 춘천시 강원대학길1 의생명과학대학 Tel : 033)250-7601-2 FAX : 033)259-5640
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