이득찬 교수
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이득찬 교수

이득찬 교수님
이득찬 교수
  • 전공 : 면역학
  • 전화번호 : 직장 033) 250-6488
  • E -mail : dclee@kangwon.ac.kr
  • 연구실 : 의생명과학관 A-216 (면역학 실험실 : B-224호)
학력
  • 학사:강원대학교 생물응용공학과 1990.03 – 1996.02
  • 석사:강원대학교 대학원 생물응용공학과 1996.03 – 1998.02
  • 박사:일본 동경대학 대학원 응용동물전공(면역학) 2000.10 – 2003.09
주요경력
  • 박사후 연수과정 : 일본 동경대학 의과학연구소 인간질환모델연구센터 (2003.10-2006.03)
  • 박사후 연수과정 : 포천 중문의과대학 기초의학연구소 (2006.01 – 2007.03)
  • Research Associate : Perinatology Research Branch, USA (2007.09 – 2011.07)
  • 강원대학교 링크 사업단 기업지원 부장 (2012. 03 - 현재)
연구분야
  • 임신관련 질환 연구, 면역관련 기능성 소재연구
연구실적
1) 학위논문
  • The studies on the anti-apoptotic function of cellular prion protein using truncated prion proteins.

2) 정기학술지
  • Impact of dietary fat sources and feeding level on adiposetissue fatty acids composition and lipid metabolism relatedgene expression in finisher pigs. Animal Feed Science and Technology, 196, 60-67 (2014)
  • Trophoblast islands of the chorionic connective tissue (TICCT) : A novel placental histologic feature. Placenta, 34, 360-368 (2013)
  • Endoglin in amniotic fluid as a risk factor for the subsequent development of bronchopulmonary dysplasia. American Journal of Reproductive Immunology, 69, 105-123 (2013)
  • Glycogen phosphorylase isoenzyme BB plasma concentration is elevated in pregnancy and preterm preeclampsia. Hypertension, 59(2), 274-282 (2012)
  • Protein profiling underscores immunological functions of uterine cervical mucus plug in human pregnancy. Journal of Proteomics, 74(6), 817-828(2011)
  • miR-210 targets iron-sulfur cluster scaffold homologue in human trophoblast cell lines: siderosis of interstitial trophoblasts as a novel pathology of preterm preeclampsia and small-for-gestational-age pregnancies. American Journal of Pathology, 179(2), 590-602(2011)
  • Chronic chorioamnionitis displays distinct alterations of the amniotic fluid proteome. Journal of Pathology, 223(4), 553-565(2011)
  • A molecular signature of an arrest of descent in human parturition. American Journal of Obstetrics and Gynecology, 204(2):117, e15-e33(2011)
  • Evidence for a spatial and temporal regulation of prostaglandin-endoperoxide synthase 2 expression in human amnion in term and preterm parturition. Journal of clinical endocrinology and metabolism, 95(9), E86-E91(2010)
  • Surfactant protein-A as an anti-inflammatory component in the amnion: implications for human pregnancy. The Journal of Immunology, 184(11), 6479-6491(2010)
  • Widespread microbial invasion of the chorioamniotic membranes is a consequence and not a cause of intra-amniotic infection. Laboratory Investigation, 89, 924-936(2009)
  • Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. The Journal of Immunology, 182(6), 3919-3927(2009)
  • Expression patterns of microRNAs in the chorioamniotic membranes: a role for microRNAs in human pregnancy and parturition. Journal of Pathology, 217, 113-121(2009)
  • Honey major protein characterization and its application to adulteration detection. Food Research International, 41, 952-956(2008)
  • NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling. Biochemical and Biophysical Research Communications, 359(1), 76-82(2007)
  • Neurotoxic prion protein (PrP) fragment 106-126 requires the N-terminal half of the hydrophobic region of PrP in the PrP-deficient neuronal cell line. Protein and Peptide Letters, 14(1), 1-6(2007)
  • Fusion of Doppel to octapeptide repeat and N-terminal half of hydrophobic region of prion protein confers resistance to serum deprivation. Microbiology and Immunology, 50(3), 203-209(2006)
  • Octapeptide repeat region and N-terminal half of hydrophobic region of cellular prion protein possess anti-apoptotic function. Veterinary Biochemistry, 42, 19-22(2005) Japanese
  • Cell-autonomous PrP-Doppel interaction regulates apoptosis in PrP gene-deficient neuronal cells. Biochemical and Biophysical Research Communications, 333, 448-454(2005)
  • PrP cooperates with STI1 to regulate SOD activity in PrP-deficient neuronal cell line. Biochemical and Biophysical Research Communications, 328, 14-19(2005)
  • Octapeptide repeat region and N-terminal half of hydrophobic region of prion protein (PrP) mediate PrP-dependent activation of superoxide dismutase. Biochemical and Biophysical Research Communications, 326, 600-606(2005)
  • Cellular prion protein regulates intracellular hydrogen peroxide level and prevents copper-induced apoptosis. Biochemical and Biophysical Research Communications, 323, 218-222(2004)
  • Prion protein suppresses perturbation of cellular copper homeostasis under oxidative conditions. Biochemical and Biophysical Research Communications, 313, 850-855, (2004)
  • Tumor necrosis factor attenuates prion protein-deficient neuronal cell death by increases in anti-apoptotic Bcl-2 family proteins. Biochemical and Biophysical Research Communications, 310, 725-729(2003)
  • Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line. Biochemical and Biophysical Research Communications, 308, 660-667(2003)
  • Screening of hexavalent chromium biosorbent for marine algae. Applied Microbiology and Biotechnology, 54, 445-448(2000)
  • Purification of peroxidase from chinese cabbage roots by reverse micelle system. Journal Microbiology and Biotechnology, 8, 466-470(1998)
  • Discrimination of native bee-honey and foreign bee-honey by SDS-PAGE. Korean Journal of Food Science and Technology, 30, 1-5(1998) Korean
  • Characteristics of native bee-honey harvested in Kangwon-area. Korean Journal of Food Science and Technology, 29, 1082-1088(1997) Korean

3) 단행본

4) 연구보고서
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