Cellular Immunology Laboratory
The goal of my research is to understand the differentiation programs of T and B lymphocytes at cellular and molecular levels. Particularly, defining metabolic pathways that enable to generate follicular helper T cells and plasma cells is my current interest. Engineering T cells to express chimeric antigen receptor (CAR) and application of the CAR-T cells against various cancer models are also my research topics. Moreover, I am open to adopting other experimental approaches to achieve my research goals and this will be facilitated by collaborating with scientists working in other research areas.
Major research areas
- Defining metabolic pathways controlling germinal center reaction
- Engineering CD4+ or CD8+ T cells to express Chimeric Antigen Receptor (CAR)
- Establishment of CAR-T protocol using in vivo model systems against various cancers